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Hamilton, GA
A 50-year-old female asked:

On humira q 14 days x 8 months ra. it is losing effectiveness. adding plaquenil (hydroxychloroquine) 200mg bid. is this a good approach? when will i begin to feel better?

2 doctor answers5 doctors weighed in
Dr. Ronald Krauser
A Verified Doctoranswered
A US doctor answeredLearn more
Not really: Methotrexate or Arava (leflunomide) would be much better options as additions to humira. If that does not work, one can always change to another biologic but i would increase the Humira injections to once weekly before giving up on it.
Dr. Pierre Moeser
Specializes in Rheumatology
Good idea: Yes, addition of Plaquenil (hydroxychloroquine) makes sense but the Plaquenil (hydroxychloroquine) may take 1-2 months to kick in. There may some factors (weather, stress) that are making your RA worse instead of the Humira failing.

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Last updated Jul 3, 2014

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