U.S. doctors online nowAsk doctors free
Hamilton, GA
A 50-year-old female asked:

On humira q 14 days x 8 months ra. it is losing effectiveness. adding plaquenil (hydroxychloroquine) 200mg bid. is this a good approach? when will i begin to feel better?

2 doctor answers5 doctors weighed in
Dr. Ronald Krauser
A Verified Doctoranswered
Rheumatology 54 years experience
Not really: Methotrexate or Arava (leflunomide) would be much better options as additions to humira. If that does not work, one can always change to another biologic but i would increase the Humira injections to once weekly before giving up on it.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Pierre Moeser
Specializes in Rheumatology
Good idea: Yes, addition of Plaquenil (hydroxychloroquine) makes sense but the Plaquenil (hydroxychloroquine) may take 1-2 months to kick in. There may some factors (weather, stress) that are making your RA worse instead of the Humira failing.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Jul 3, 2014

Disclaimer:

Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.