A member asked:

Can two parents with positive blood types have a negative blood type baby?

3 doctors weighed in across 2 answers
Dr. Juan Merayo-Rodriguez answered

Specializes in Pathology

Yes it could: Someone who is "rh positive" or "rh+" has at least one rh+ allele, but could have two. Their genotype could be either rh+/rh+ or rh+/rh-. Someone who rh- has a genotype of rh-/rh-. A father who is rh+ could pass either an rh+ or rh- allele to his son or daughter. And the same from rh+ mother if genotype is rh+/rh-. The children have 25% chance of having rh-.

Answered 10/11/2017

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Dr. Richard Pollard answered

Specializes in Anesthesiology

Maybe: Rhesus transmission (+ or -) is not a clear as the ABO transmission. This is purely a result of the genetic expression of each parent, and this may be different when their genes are combined in a new child.

Answered 4/24/2015

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