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Cary, NC
A 52-year-old female asked:

on opana 10 mgs ir at night for severe rls. not lasting through the night. can opana er be taken once a day? would this cause daytime withdrawal s/s?

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Dr. Donald Jacobson
A Verified Doctor answered
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OpanaIR lasts on : Average between six and 13 hours with the average being somewhere around eight. Opana er lasts between six and 36 hours. I would talk to your sleep specialist about this. Having a narcotic in your system around the clock is probably not in your best interest. Switching to another narcotic may indeed be a better answer. Another possibility would be a slight increase in the dose of the ir form. Best wishes.

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Last updated Apr 7, 2016

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