What is relation between severe depression and macrocytic anemia. i ate very little for year and lost 10 kg but all vit. test ok. am 70 yrs?

None Known; 2 Issues: Depression is a soul, mind, brain issue based on internalized beliefs from past events ; in response to current life events. Anemia = ?ed red blood cell concentration. Macrocytic means red blood cells are larger than usual; is often associated with ?ed B12 ;/or folate (folic acid). As complex creatures we always have a huge number of issues going on; they do not necessarily have any direct/causal relationship.

Not directly.: There is no direct correlation . Depression can cause poor nutrition due to loss of appetite and when depressed long enough can cause marked debility due to malnutrition. Pernicious anemia is caused by the lack of intrinsic factor in the stomach which causes malabsorption of essential vitamins especially b12. B12 can be better absorbed by using sublingual drops or subcutaneous injections.