A 41-year-old female asked:

What is stronger, morphine sulfate or methadone? i'm getting tolerant to 100mg of morphine 3x/day & need a break, hoping to find something equal.

1 doctor answer1 doctor weighed in
Dr. Pavel Conovalciuc
Family Medicine 25 years experience
Methadone vs. MS: Methadone is definitely stronger than the same dose of morphine, but to switch from one to another you need to talk to your doc about that. Methadone has been falling out of favor for pain purposes due to its short duration of analgesic effect and multiple side effects.
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Last updated May 15, 2019


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