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A member asked:
My wife went to a women's health doctor and was prescribed sulfameth/trimethoprim 800/160. is it safe to take if pregnant or trying to conceive?
A doctor has provided 1 answer
TMP/SMX: Animal studies have shown fetotoxicity and teratogenicity. No controlled data in human pregnancy. Both drugs cross the placenta. In 186 pregnancies, the mother received either placebo or tmp-smx in a retrospective study. The incidence of congenital abnormalities was 4.5% with placebo and 3.3% with tmp-smx. No abnormalities were reported in women who were treated in the first trimester.
Answered 3/2/2014
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