Can anxiety lead to gastroesophageal reflux disease?

Not really, but...: Excessive anxiety complicates and amplifies most problems, both physical and emotional. So ger may seem worse, you might "notice" it more, react more to the symptoms. Further, it's possible that ongoing stress may exacerbate conditions which lead to ger, such as acid content in the stomach, gastritis, drinking alcohol, smoking, late-night eating, caffeine intake, over-eating, etc.