Is cyclophosphamide good to reduce tumor?

While these agents: (alkylators) were the standfast drugs from the 1960's, their main role now is in very high doses prior to bone marrow or stem cell transplants. They reduce some cancers, particularly lymphoma and perhaps breast cancer, but the class is limited by marrow toxicity, resistance, and late effects. It can reduce some tumors, very few, but is usless in many.