A member asked:

In what ways can cancer cells escape programmed cell death?

A doctor has provided 1 answer

Mutations: Several of the known mutations that contribute to the malignant phenotype work by opposing the normal mechanisms of apoptosis. The discovery of bcl2 mutations driving lymphoma was the first of many. Here's a now-classic paper http://carcin.Oxfordjournals.Org/content/21/3/485.Full.

Answered 3/23/2014

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