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A member asked:
What are the ways that cancer cells begin to grow?
A doctor has provided 1 answer
Sequential mutations: series of gene changes usually beginning with p53 giving immortality to the cell. Then genes induce oncofetal proteins which function to allow fetus to mature and then turn off. Post translational modifications in the proteins of these genes which have been demethylated by virus or carcinogen lead to cells producing the cancer protein and then phenotypically change to the malignancy.
Answered 6/12/2017
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