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Austin, TX
A 33-year-old male asked:

What causes chronic nasal congestion which responds to afrin but not astelin, flonase, or sinus rinses? can surgery even work in a case like this?

1 doctor answer1 doctor weighed in
Dr. John Chiu
Allergy and Immunology 58 years experience
Afrin (oxymetazoline) rebound: Afrin (oxymetazoline) causes severe narrowing of the blood vessels in the nose and thus the effect on decongestion. However prolonged constriction leads to decrease blood supply to the tissue and may lead to permanent damages. The nose also becomes less responsive to afrin (oxymetazoline) with prolonged use . Flonase counteracts inflammation and Astelin is an antihistamine and neither constricts the blood vessels.
Last updated Jan 26, 2018

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