Is rifaximin a board spectrum rx? how likely can it cause a clostridium diffclie infection? head it can treat it?

Low risk for C. Diff: Rifaximin is a semisynthetic antibiotic based on rifamycin, which has a broad spectrum. After initial decrease in the GI flora (enterococcus, escherichia coli, lactobacillus, bacteroides and clostridium perfringens), normalization is seen after 1 month. In one study of 211 patients given Rifaximin chronically for 8 months, no patient tested positive for c. Difficle, but the possibility exists.