My husband feels like his nipples are being twisted what could cause this and it's in both nipples at the same time?

See your doctor: It is not clear what the symptoms are but clearly he needs to be examined. I have not heard of that as a side effect of zantac (ranitidine) but regardless, he needs to see his primary care doctor.

See your Dr.: I suggest your see his primary care physician for further evaluation of his complaint good luck , hope he feels better.

Musculoskeletal?: Intermittent anterior chest wall pain in an early thirties male suggests pectoralis muscle strain, perhaps from excess physical activity. His age would seem to discount angina pectoris, but this is always of concern in males, especially if there is history of elevated cholesterol. A doctor visit seems to be in order. If the pain becomes constant, then urgent evaluation is necessary.