Could cryofibrinogenemia cause multiple t2 hyperintensities in the periventricular and deep white matter of the brain?

MRI CORRELATION: Your report of your imaging causes me some concern, as it is a description consistent with several entities, and these include microvascular angiopathy (small vessel arteriolosclerosis), binswanger's encephalopathy, but could even be correlated with ris (asymptomatic ms). I am unable to state that cryofibrinogenemia can be considered a good answer here. You may need further testing to answer.

Mixed cryoglobulin: Most of the literature regarding cryoglobulinemia and neurologic complications is in reference to peripheral neuropathies and not central nervous system dysfunction. Hence, another cause should be sought for the mr abnormalities. Good luck and well wishes.