A member asked:

Why is my md suggesting genetic testing to help determine if i should wait or have surgery soon on my 4.9 thoracic aortic aneurysm?

4 doctors weighed in across 2 answers

Earlier surgery: May be indicated in patients with individuals with confirmed mutations in tgfbr2 and tgfbr1genes and/or a family history of aortic dissection with minimal aortic enlargement. This is something you and your doctor should discuss.

Answered 1/24/2014

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Dr. Craig Carter answered

Specializes in Thoracic Surgery

Cause: Aortic aneurysms caused by genetic predisposition can have a much higher rupture rate and a more rapid rate of growth. These are operated on at a smaller size. Otherwise, 5- 5.5cm is the usual size to consider surgery. If there is a family history, or if the genetic testing is positive, family members should be tested.

Answered 1/2/2015

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