Results may vary: 1 mg bid klonepin should be generally noticeable unless there is some tolerance to benzos or alcohol. Generally the zoloft (sertraline) may take a few weeks to a month to be effective, and has the advantage of fewer risks complications such as addiction and tolerance, sedation, etc. About 70% of people w/ panic disorder can be reduced or discontinued from meds w cognitive behavioral therapy.
Answered 4/3/2016
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