A member asked:

Genetic disorder methemoglobinemia (blue person disease), can you tell me more?

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Dr. Anna-Kaisa Niemi answered

Specializes in Clinical Genetics

Methemoglobinemia: Methemoglobinemia is called "blue man disease" because blood has a blue tint (instead of red) due to methemoglobin. It can be caused by ingestion of certain drugs or compounds. A genetic form is due to nadh-cytochrome b5 reductase deficiency (an enzyme) which causes decreased oxygen carrying capacity of the blood, with resultant cyanosis (=blueness) and hypoxia (low oxygen in blood).

Answered 5/8/2015

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