Could you tell me about primary immune deficiency and secondary immune deficiecy?

Genetic/acquired: The easiest way to describe the differences between primary (born with based on genetics or gene mutations) and secondary (associated with for example someone on chemo or any process or disease state that induces a malfunction in the immune response). Stress can actually cause a compromise of the immune system or severe diarrhea can cause antibodies to be lost resulting in secondary immune probs.