A 48-year-old member asked:
I was wondering what are 4 neurotransmitters affected by tricyclics antidepressants?
2 doctor answers • 3 doctors weighed in
Psychiatry 43 years experience
4.6k viewsReviewed >2 years ago
Psychiatry 45 years experience
Primarily 2 affected: Tricyclic antidepressants like amitriptyline, imipramine, desipramine, nortriptyline, clomipramine, doxepine, protriptyline, trimipramine, among others, primarily act to increase serotonin ; norepinephrine but with some also affecting to a lesser degree Dopamine ; histamine. Mono-amine-oxidase-inhibitor (maoi), Parnate (tranylcypromine) (tranylcipramine), affects serotonin, epinephrine, norepinephrine, ; dopamine.
4.6k viewsAnswered >2 years ago
Last updated Jun 30, 2014
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