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Miami, FL
A 34-year-old female asked:

How does phentermine works in the body? what neurotransmitters are affected the most? also what are the withdraw symptoms and how long they usual last

1 doctor answer1 doctor weighed in
Dr. Tracie Leonhardt
Emergency Medicine 30 years experience
Phentermine : Phentermine mechanism of action is to release norepinephrine which works on the hypothalamus of the brain to reduce hunger. It also to a smaller extent releases Dopamine and serotonin. It is thought to also inhibit reuptake of Dopamine and seratonin. Most of any withdraw symptoms would be increased hunger and fatigue. These symptoms usually last for 2-3 days or up to a couple of weeks.

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Last updated Sep 28, 2016

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