A member asked:

Help docs! i'm trying to find out what causes alzheimer's disease?

5 doctors weighed in across 2 answers

We are too!: No one knows what causes alzheimers disease. Age is the main variable: the older the person, the more likely. Family history ; heredity are factors too. However, all of these are out of our control. Looking at controllable factors, past brain injury and cardiovascular health seem to increase risk. See: http://www.Alz.Org/alzheimers_disease_causes_risk_factors.Asp.

Answered 4/17/2016

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Complex: The abnormal deposition of amyloid and tau protein in the brain. We are not sure what starts the cascade of inflammation and neuronal damage . It is a complex mechanism - partially genetically based- but likely environmental as well. Present therapies focus on boosting chemicals in the brain that become deficient. Future therapies will remove abnormal protein and prevent their deposition.

Answered 1/2/2015

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