What is the most frequent transfusion associated disease complication of blood transfusion?

Bacterial in PLT: Transfusion is safer today than ever, but as any other intervention in medicine has risks associated with it. The infectious disease most commonly associated with transfusion is bacterial contamination in platelet components about 1 in 12, 000 transfusions. To put it in perspective HIV is about 1 in 2 million. The most common adverse event (1%) is fever and hives along with volume overload (taco).