Hello docs, is asd (atrial septal defect) hereditary?

In some cases: Some cases of atrial septal defect have a genetic component. An example is holt-oram syndrome which is caused by a mutation in the tbx5 gene. Tbx5 codes for a protein called t-box 5, which is a transcription factor active during fetal development and is important in the proper development of the heart and the upper extremities. Almost certainly, there are other important genes.