A member asked:

Why does morphine make me itchy? would benadryl (diphenhydramine) help?

3 doctors weighed in across 2 answers

Morphine itch: Taking morphine can be very dangerous. Talk to your doctor about why you are taking morphine and about any reactions

Answered 10/10/2017

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Dr. John Chiu answered

Histamine release: Opiates including morphine releases histamine from cells and thereby causing itching. Long-term use of morphine should be avoided unless you have a terminal disease.

Answered 12/20/2013

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