My husband has klinfelters and we starting ivf to have a baby. i am wonder if it is inherited or can our child be affected from it. eg down syrdome?

Genetic counseling: It is very important you and your husband speak with a genetic counselor about the possible risks associated with doing ivf when the father has klinefelter syndrome. The likelihood of passing on a chromosomal abnormality is difficult to predict, and some recommend preimplantation testing. See http://emedicine.Medscape.Com/article/945649-treatment for more info. I wish you both the best.

Klinfelter's: Klinfelter's syndrome is a chance happening and is not inherited.