A member asked:

Been reading that viibryd (vilazodone hydrochloride) most resembles the ssri paxil plus buspar...is this correct?

4 doctors weighed in across 2 answers

Almost: It's mechanism of action is that of an ssri which i would characterize more to be like zoloft (sertraline) in effect and the action of buspirone. However, it does not have the indication for the treatment of any anxiety disorder and the studies have not been done yet to see whether it has a generalized anxiety benefit or not. Best wishes.

Answered 9/29/2016

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Viibryd: is a selective serotonin reuptake inhibitor (SSRI) & 5HT1A receptor partial agonist. It has an FDA indication for treatment of Major Depressive Disorder (MDD). Paxil is SSRI & it has FDA indications for tx of MDD, Panic D/O, Obsessive Compulsive D/O, PTSD, Generalized Anxiety D/O & Social Anxiety D/O. I don't necessarily agree that Paxil +Buspar are most like Viibryd.

Answered 11/24/2018

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