A member asked:

What amount of does take to get high off of diphenhydramine hci/antihistamine and how long does it take to kick in?

4 doctors weighed in across 2 answers

Antihistamine: What are you taking it for? The answer depends on what you are treating

Answered 7/17/2014

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Varies: Varies with dose. Some people get sleepy at lower dose than others. Some people get jumpy instead, especially children. Also depends on interaction with other meds or alcohol or caffeine.

Answered 5/27/2014

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