A member asked:

What is haloperidol's mechnism of action?

2 doctors weighed in across 2 answers

Haldol (haloperidol) action: Haloperidol is a typical butyrophenone type antipsychotic that exhibits high affinity Dopamine d2 receptor antagonism and slow receptor dissociation kinetics.[49] haloperidol's negligible affinity for histamine h1 receptors and muscarinic m1 acetylcholine receptors. En.Wikipedia.Org/wiki/haloperidol.

Answered 7/3/2020

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Haloperidol: You got an excellent response from Dr. Jacobson. Mine is a little simpler - it block postsynaptic dopamine (D2) receptors (mesolimbics).

Answered 7/3/2020

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