A member asked:

Is sam e safe during pregnancy? highrisk due to pots, partialplacenta previa and ehlersdanlos and it is causing lots of anxiety and some depression.

A doctor has provided 1 answer
Dr. Pamela Pappas answered

Specializes in Psychiatry

SAM-e: Sam-e is not recommended in the first trimester or during breastfeeding due to a lack of studies. It's been used in the third trimester for women with intrahepatic cholestasis of pregnancy. http://tinyurl.com/m86fras it was well-tolerated in the moms and incidence of premature labor was 2/15 vs 5/15 in the placebo group. Very small study which was also very short. Please discuss with your ob.

Answered 12/4/2013

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Is there treatment for depression and anxiety during pregnancy?

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