Basic lab medicine: A small amount of the substance, which is coded by the normal genome, is ordinarily present in the bloodstream. Immunoassays also detect antigens similar to ca125 as weak signals, and a cutoff is established below which a reading is not suspicious for cancer. These facts have a lot to do with why these markers aren't all that helpful in searching for cancers in folks without any signs.
Answered 4/10/2014
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