I have mild spondylolistheia in l5-s1. could this cause pins and needles in legs, tight hamstrings?

Yes it could.: We'll get evaluated by a spinal specialist. If your spondylolisthesis is associated with a herniated disc for example, it could lead to pins/needles and pain down the legs. You need to see a spine specialist for examination and treatment. The first line of treatment focuses on physical therapy, nsaids, and possibly epidural injections.

Mild: If this is mild, then it wouldn't be suggestive, but it all depends on the definition. Presumably a MD ordered this scan, so you should go over the results in detail with them in order to determine if this is the source of the issue.