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A 22-year-old male asked:

Best first-line treatment for mantle cell lymphoma now: high doses of ara-c+rituximab and autologous sc transplant, or rituximab+bendamustine?

1 doctor answer1 doctor weighed in
Dr. Michael Dugan
Specializes in Hematology
There is no: Definitive answer to your question. Studies have compared the strategies you mention. The high dose ara-c arm was closed because it was difficult to mobilize stem cells for transplant after these regimens. Bendamustine-r is a good program, and many centers would consolidate a good response with an autograft.

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Last updated Nov 24, 2013

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