Need doctor's help! will natural progestetone cream cause acne?

Possibly: Although we see some benefit in acne treatment in some women who take combination oral contraception pills (which contain some degree of progestin), progestin-only pills and injections have been known to exacerbate acne. I would be suspicious that this would also apply to a progesterone cream, so it's possible, especially if you've noticed more acne since starting use of the cream