Is it possible for me to take a decongestant with claritand?

Yes: They do different things. An antihistamine, like Claritin should help block the release of histamine from mast cells, decreasing mucous production. Decongestants cause swelling and congestion to decrease inside the nose. These are complimentary medicines and are often prescribed together for significant relief of congested runny nose associated with allergies, colds and even nasal infections.