Pr er and cerbb2 all negative stage 1b full mastectomy with recon size 0.8 cm invasive lobular casinoma in situ do not want chemo what's yr opinion?

Not clear: This is difficult to answer without examining you, seeing the pathology report and other studies. You question is a little confusing because you mention invasive and in-situ in the same sentence. If your doctors are recommending chemo and you disagree, i highly recommend you go to another breast center to get a 2nd opinion.

Not usually needed: Breast cancer is very complicated and there are many variables, so hard to say in your particular case. But generally, lcis is usually considered a marker for increased risk of an invasive cancer in both breasts (at equal risk). Invasive lobular carcinoma is treated like "regular" or ductal carcinoma. Your post seems contradictory (it can't be both in situ and invasive). Would need more info.