A member asked:

Can i take xl3 for my cold and a bit later my alprazolam?

2 doctors weighed in across 2 answers

Xl3 + Xanax (alprazolam): This contains tylenol, (acetaminophen) phenylephrine (decongestant), and clorpheniramine maleate (antihistamine). The phenylephrine may keep you awake, so taking the xanax will help counteract that, the Chlorpheniramine Maleate is a mildly sedating antihistamine. You can take the xanax, but i would not work around dangerous machinery or drive afterwards until you see how they interact. I don't expect any problem.

Answered 6/24/2014

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Careful: Xl3 has a sedating antihistamine - chlorpheniramine - which will have additive effects with alprazolam. If it's tonight before bed you'll be okay, just don't drive or anything while using both.

Answered 7/11/2015

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