Can you take prednisone and solumedrol (methylprednisolone) iv at the same time?

See below: Yes, for a short period of time only.

Makes little sense: It really makes no sense to take both forms of systemic corticosteroids at the same time.

Steroids: Prednisone and methylprednisolone are not exactly the same in their effects. It is possible that the prednisone is supplementing a different steroid effect than that provided by methylprednisolone. Please discuss with your doctor, especially if the meds are coming from different doctors.

Would modify: This is NOT standard protocol. Efficacy is similar but risk of adverse effects will be higher. Get a second opinion