A member asked:

What is the warfarin disease?

3 doctors weighed in across 2 answers

Warfarin: Warfarin (coumadin) is a drug used to prevent blood clots. A rare but serious complication resulting from treatment with warfarin is warfarin necrosis, which occurs more frequently shortly after commencing treatment in patients with a deficiency of protein c. Since warfarin initially decreases protein c levels faster than the coagulation factors, it can increase the blood's tendency to clot.

Answered 9/28/2016

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Don't know: I googled "warfarin disease" and couldn't find anything other than warfarin necrosis which is a condition that occurs in some people who are treated with warfarin (a blood thinner). Within a few days of starting treatment, a paradoxical increase in clotting can occur in some individuals leading to skin/sq fat death. Typically this occurs in obese, middle-aged women.

Answered 3/21/2015

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