Alternatives to diamox (acetazolamide) for altitude illness?

Not really: Fundamentals include gradual ascent, graded exercise, prevention of dehydration, avoidance of alcohol and prompt recognition of symptoms. Acetazolamide (diamox) is the cornerstone of phrmacotherapy for prevention, but Dexamethasone is often used in treatment of acute illness.

Other choices: In mild sulfa allergy, Diamox (acetazolamide) (a sulfa medicine) can be tested and possibly used. If not safe, or intolerable side effects other choices do exist. Dexamethasone can be taken in preventative fashion--not only for treatment. Recent studies show certain doses of Motrin are beneficial in reducing incidence as well. Altitude illness-if present--can be fatal. Go lower as first line treatment.