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A 21-year-old member asked:

What neurotransmitters are important in addiction?

3 doctor answers15 doctors weighed in
Dr. Jeff Blixt
Addiction Medicine 25 years experience
Many: Dopamine drives every addiction, it is the end point, and most important in driving the behavior of repetitive use of the substance.It controls the motivation to use. Past Dopamine their is a long list that affect all aspects of addiction, withdrawal and relapse. Endorphins, serotonin, glutamate, gaba, endocannabinoids, norephinephrine, crf. These are the other major "players" in addiction.
Dr. Vasu Brown
Integrative Medicine 35 years experience
Dopa: Dopa receptors - learn more how this happens here - http://learn.Genetics.Utah.Edu/content/addiction/drugs/.
Dr. Byron Law-Yone
Psychiatry 56 years experience
Also, glutamate, sertonin, GABA, norepinephrine
Sep 15, 2013
Dr. Dheeraj Raina
Psychiatry 30 years experience
Dopamine: While various addictive substances may have different particular neurotransmitters they first act on, their addictive nature is the result of a cascade of effects leading to the final common pathway of triggering Dopamine release in particular parts of the brain that fuel a sense of pleasure and reward.

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Last updated Oct 15, 2017
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