A member asked:

Is it safe to take 4mg of lunesta (eszopiclone) in conjunction with 4mg of periactin to help me sleep. i suffer from ptsd, chronic insomnia, adhd.

A doctor has provided 1 answer
Dr. Patrick Tapia answered

Specializes in Psychiatry

Heavy: This is a powerful regimen for sleep. I think that the use of eszoplicone chronically may lead to cognitive disturbances that are hopefully reversible with discontinuation. Additionally, antihistamines used chronically can lead to weight gain or cognitive impairment as well. Talk with your doctor about any concerns and as always try to implement sound sleep hygiene before you go to sleep!

Answered 10/16/2017

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