Can Be Taken Anytime: Some statins (pravachol, zocor, (simvastatin) mevacor) have very short half-lives (2-4 hours) and have a better effect if taken at night. This is because the medication works by decreasing cholesterol synthesis which is increased during the evening hours. Other statins (lipitor, crestor) have very long half-lives (14-18 hours) and have equal effect if taken in the morning or evening.
Answered 5/11/2018
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