Variable 7-10 days: The half life of nicotine metabolite, cotinine, is, on average 16 hours, but there are many factors affecting the blood level. A safe interval would be about 7 days. Note that urine may test positive even longer. See this site for more info. http://www.ncbi.nlm.nih.gov/pmc/articles/pmc2953858/.
Answered 11/3/2013
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