Can ciprofloxacin hcl work for tooth ache?

probably not: Cipro (ciprofloxacin) is not normally used for toothache relief. If there is an infection, an exam by a dentist is necessary to evaluate and diagnose. There are better antibiotics to use. Do not self medicate with antibiotics used for other conditions.

Yes, but...: Yes, it's an antibiotic so can help, but you should always have a painful tooth checked to find out why it hurts. Some antibiotics work better than others for different infections.

Antibiotics: Antibiotics can help control the spread of infection, but will not "cure" a damaged tooth. There are many other antibiotics more effective in this role than cipro (ciprofloxacin). To fix your problem will require filling, root canal treatment, and/or extraction. Please don't self-medicate...See your dentist before this gets out of control.