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Sugar Land, TX
A 36-year-old male asked:

My wife is on paxil (paroxetine) 20mg 1x/day for ocd. last couple weeks lots of water retention and edema in legs. pcp says it's paxil (paroxetine) side efx. is this possible?

1 doctor answer4 doctors weighed in
Dr. Pamela Pappas
Psychiatry 43 years experience
Possible but rare: Peripheral edema happens in 0.1-1% of people, making it a rare, but possible side effect. Even more rarely (<.1%) people can develop inappropriate ADH (vasopressin) secretion and low sodium. I see that these are being checked for in labs. There are other, much more common, causes for peripheral edema also, though.
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Last updated Jun 10, 2014

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