A member asked:

My wife is on paxil (paroxetine) 20mg 1x/day for ocd. last couple weeks lots of water retention and edema in legs. pcp says it's paxil (paroxetine) side efx. is this possible?

A doctor has provided 1 answer
Dr. Pamela Pappas answered

Specializes in Psychiatry

Possible but rare: Peripheral edema happens in 0.1-1% of people, making it a rare, but possible side effect. Even more rarely (<.1%) people can develop inappropriate ADH (vasopressin) secretion and low sodium. I see that these are being checked for in labs. There are other, much more common, causes for peripheral edema also, though.

Answered 6/10/2014

4.8k views

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