Question 1

which type of mutation causes down syndrome?

Accepted Answer

No : Down syndrome is an abnormality of chromosome numbers, not a trait or mutation in the gene code. During conception only one of chromosome of each pair is given by both parents to the fertile egg.If a parent adds their  2 nbr 21chm to the other parents nbr 21, 3 end up in the egg ; the excess 21 causes the  all the problems.Rare forms are causes by a extra piece of a 21, but that's another issue.

Question 2

which type of chromosomal mutation causes down syndrome?

Accepted Answer

Trisomy 21: Down syndrome is also called trisomy 21.  That means that there is a partial or complete third copy of the chromosome 21.  It is the most common chromosomal abnormality.

Question 3

can you show me more than 5 syndromes that are cause by dna mutation such as down syndrome, etc?

Accepted Answer

Here you go: Edwards syndrome, cre du chat syndrome, angelmann syndrome, turner syndrome, klinefelter syndrome, just to name 5 on the top of my head.

Question 4

is there a type of mosaic down syndrome that doesn't require the mutation to come from either parent to have a downs child?

Accepted Answer

Yes: A mosaic Down syndrome child can come from a normal egg and normal sperm, produced by normal parents. The fertilized egg would start out normal with 46 chromosomes. It can divide into 2 normal cells, which themselves divide again. If on one of the early divisions, one cell ends up with an extra #21 chromosome and survives to continue dividing, the child will be mosaic with some trisomy 21 cells.

Question 5

will cystic fibrosis mutation test detect down syndrome during pregnancy?

Accepted Answer

Separate study: If you are having the one study done it is simple enough to arrange for the other study at the same time. They are separate tests and often done at a separate lab.

Question 6

does teething cause down syndrome?

Accepted Answer

No: Down syndrome is a genetic problem and has nothing to do with teething.

Question 7

what causes high risk of my little one having down syndrome?

Accepted Answer

Advanced mom age: The risk of having a baby with any form of chromosome defect increases as the  mother ages. It is lowest in her early 20's and rises above 1% at 40 and approach 5% at 50. It is a fact of life, that environmental toxic factors may eventually cause changes to the eggs that yield this risk.

Question 8

is down syndrome always caused by a defect in the 21 chromosome?

Accepted Answer

Extra chromosome 21.: Either complete or partial trisomy for chromosome 21 is always responsible for down syndrome.

Question 9

what are some of the causes for a child to be born with down syndrome?

Accepted Answer

Genetics: Down syndrome is a genetic condition, meaning it is part of your cells.  It is not something inherited like the color or your eyes, but is due to a defect when the egg, sperm or embryo cell is made.  Most causes are from trisomy 21 (having three copies of the chromosome 21 instead of two).  There are no environmental or behavioral risk factors.  It is seen mostly in women of advanced age.

Question 10

what are the causes of people with down syndrome to have similar facial features?

Accepted Answer

A chromosomal proble: Downs' syndrome is usually a chromosomal problem caused by abnormality of chromosome 21.  Hence, the development of similar facial features --- eyes slanted, low set ears, broad, larger mouth with broad large tongue; coarse hands with an unusual crease in the palm; some form of mental retardation -- all are a result of the chromosomal problem.  Many will have congenital heart disease as well.

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Doctor answers about:

What type of mutation causes down syndrome

A member asked:

Which type of mutation causes down syndrome?

A member asked:

Which type of chromosomal mutation causes down syndrome?

A member asked:

Can you show me more than 5 syndromes that are cause by dna mutation such as down syndrome, etc?

A member asked:

Is there a type of mosaic down syndrome that doesn't require the mutation to come from either parent to have a downs child?

A member asked:

Will cystic fibrosis mutation test detect down syndrome during pregnancy?

A member asked:

Does teething cause down syndrome?

A member asked:

What causes high risk of my little one having down syndrome?

A member asked:

Is down syndrome always caused by a defect in the 21 chromosome?

A member asked:

What are some of the causes for a child to be born with down syndrome?

A member asked:

What are the causes of people with down syndrome to have similar facial features?

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