Question 1

wat is mantle cell lymphoma?

Accepted Answer

Mantle cell lymphoma: Is a less common b-cell disease in the non-hodgkin's lymphoma group.  It tends to be advanced stage when diagnosed, and can have a propensity to involve both the gut and skin. About 20% of cases behave indolently, and treatment is quite effective at diagnosis.  Late relapses are common, and treatment is more challenging the second time around.

Question 2

has any one out there survived mantle cell lymphoma?

Accepted Answer

Definitely Yes: Mantle cell lymphoma responds very well to conventional chemotherapy but has a propensity to relapse. Incorporation of maintenance treatment or autotransplant has prolonged remissions and survival but a stem cell transplant using a matched sibling or unrelated donor can lead to a cure albeit with potential complications from graft-versus-host disease.

Question 3

does anyone know the prognosis for mantle cell lymphoma?

Accepted Answer

Depends: Mantle cell lymphoma is responsive to but probably not cured by conventional chemotherapy.  What the best treatment is, when it should include stem cell transplant, is uncertain.  If available , participate in a clinical trial.  Some patinets who are favorable can live beyond 5 years, but in others it is an aggressive disease that doesn't do well.

Question 4

what are the symptoms of end stage mantle cell lymphoma.

Accepted Answer

See below: Wekaness, possible pain, anemia symptoms, predisposition to infection, weight loss.

Question 5

for what length of time can mantle cell lymphoma go undetected?

Accepted Answer

It depends: Most lymphomas grow quite fast. That is often the case with mantle cell lymphoma too. So i would say it takes 3-6 months before the symptoms become pretty severe that we/you can not miss it easily.

Question 6

how long can mantle cell lymphoma go undetected?  where does mantle cell lymphoma show up?

Accepted Answer

A few months: We obviously don't know the natural history of such a malignancy, but suspect it is usually an aggressive process that will be clinically diagnosable within months of onset by manifesting symptoms.  As implied enlargement of lymph nodal areas will be the presentation in most cases.

Question 7

mantle cell lymphoma - is that like a hodgkin's?

Accepted Answer

Non hodgkin's: Mantle cell lymphoma is a subset of non hodgkin's lymphoma. Under microscope, it looks like clusters of small size of lymphoid cells mimicking appearance of indolent/slow-progressing lymphoma, however it behaves like an agressive lymphoma. The treatment would be combinations of chemotherapies plus biological therapy.

Question 8

what is the rang in life expectancy with mantle cell lymphoma?

Accepted Answer

Mantle cell: Lymphoma has a broad range of expected survival.  The minority of patients have an indolent course, and may not even require therapy at the time of diagnosis.  More commonly treatment is initiated with moderate to aggressive chemotherapy with duration of benefit on the order of 3-5 years.  With recurrence the management can be more challenging.

Question 9

average life span for patients with mantle cell lymphoma?

Accepted Answer

Stage ?: Depends on stage. There are two subsets of mantle cell nhl. One is an indolent subset in which 5 yr survival approaches 70-80%. The othe more aggressive subset has a prognosis of only 50/50 at three years. But stage also matters.

Question 10

what type of nodes would appear with mantle cell lymphoma or any other type of malignancy? would they be rigid and fixed or can they be soft and moveable? internist felt node but said likely benign.

Accepted Answer

Lymph node: Generally malignant lymph nodes are firm, but I have seen some that were soft and movable. If this node doesn't recede within a week or so, and if new enlarged nodes appear a biopsy would seem advisable. Discuss this with your physician and he/she will advise you about what type of follow-up is best.

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Doctor answers about:

What is mantle cell lymphoma

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Wat is mantle cell lymphoma?

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Has any one out there survived mantle cell lymphoma?

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Does anyone know the prognosis for mantle cell lymphoma?

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What are the symptoms of end stage mantle cell lymphoma.

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For what length of time can mantle cell lymphoma go undetected?

A member asked:

How long can mantle cell lymphoma go undetected? where does mantle cell lymphoma show up?

A member asked:

Mantle cell lymphoma - is that like a hodgkin's?

A member asked:

What is the rang in life expectancy with mantle cell lymphoma?

A member asked:

Average life span for patients with mantle cell lymphoma?

A member asked:

What type of nodes would appear with mantle cell lymphoma or any other type of malignancy? would they be rigid and fixed or can they be soft and moveable? internist felt node but said likely benign.

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