Question 1

is a high ana titer of  1:640 or > and symptoms present for ctd early in diagnosis likely mean a bad prognosis or not necessarily?

Accepted Answer

Not necessarily: The ANA titer will not correlate with disease activity.  Your symptoms or what organ systems that are involved early in the disease course can sometimes be predictive of how the disease will be.  If you have severe organ involvement requiring medications such Cytoxan (cyclophosphamide) that can sometimes be associated with a more worse prognosis. I hope that helps.

Question 2

hello

my ana titer test  came back as 1:320.  is this very high?.  speckled pattern.  i am quite concerned.  than you.

Accepted Answer

Is positive: This test is positive but only the doctor ordering it can explain to you the significance.  ANA tests are notoriouisly positive in people without disease.

Question 3

what causes high tsh levels? postive ana titer

Accepted Answer

Thyroiditis: Autoimmune thyroiditis is the most likely cause.

Question 4

is a ana titer of 1:640, homogenous considered high? rhuemy said i might have sle but would never diagnose in a male. should i get a 2nd opinion?

Accepted Answer

See details: That ANA is positive. If the clinical picture fits then you have sle regardless of whether you are male or female. Being a male does not exclude the diagnosis. Get a 2nd opinion if you are concerned.

Question 5

how/why can lupus symptoms present & diagnosis of lupus be made by clinical picture &high ana titer only?why don't other labs show positive?two rheum mds dx'd me.

Accepted Answer

Each person is diffe: Each person is different.  At one time a rheumatologist of evaluated the different presentations of lupus and came up with over 1400 different ones. Lab studies correlate with different manifestations.

Question 6

ana speckled pattern 1:80 with antigen detected for high sle titer,  sjordens, high titers scleroderma, crest and pbc....how worried should i be?

Accepted Answer

Need context.: We need to discuss your symptoms, what condition were you in when the blood test was taken (were you ill? Cold? Flu-like symptoms?), family history, medical conditions &amp; medications you took to properly interpret the ANA pattern. You can't base everything on the report alone, since ANA titers change with time &amp; condition. It's unlikely that you have ALL of these rare diagnoses. Use HealthTap Prime

Question 7

hx of seronegative ra yet recent labs show high crp/esr, absolute neutrophils and ana by ifa but w/ no titer. what could that mean without a titer?

Accepted Answer

See below: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, your lab results suggest active on-going inflammation. The titer of ANA is not particularly relevant.
Wish you good health.

Question 8

i just got a blood test. i have high ast & alt levels, high bilrubin, a high ck total, and a positive ana titer. can you please help me identify this?

Accepted Answer

You need a workup: You're a young man and if you exercise and feel well, I'm not concerned about the CK. Around 1 person in 4 has a positive ANA, usually low titer. Your liver tests will be repeated after 2 weeks off alcohol / meds if applicable; if still up, you'll be screened for hepatitis B and C, Wilson's, hemochromatosis and autoimmune hepatitis. Your body may simply be asking for exercise &amp; better eating.

Question 9

sm/rnp 4.3, positive ana, positive ena, ana titer 1:1280 speckled, cytoplasmic positive but low titer 1:40. always high sed rate and c-reactive protein when i am in hospital. could this be mctd?

Accepted Answer

: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that, your laboratory results are consistent with MTCD, however, autoimmune disorders often have overlapping lab results.    Wish you good health!

Question 10

what could cause high sed rate (37), high wbc, high eosinophils, high neutrophils, a high ana (54.73), ana titer 1:40? chest pain, severe fatigue?

Accepted Answer

Arthritis: You have probably have a form of arthritis. Whoever ordered the tests should be able to help you

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Doctor answers about:

What is a high ana titer

A member asked:

Is a high ana titer of 1:640 or > and symptoms present for ctd early in diagnosis likely mean a bad prognosis or not necessarily?

A member asked:

Hello my ana titer test came back as 1:320. is this very high?. speckled pattern. i am quite concerned. than you.

A member asked:

What causes high tsh levels? postive ana titer

A member asked:

Is a ana titer of 1:640, homogenous considered high? rhuemy said i might have sle but would never diagnose in a male. should i get a 2nd opinion?

A member asked:

How/why can lupus symptoms present & diagnosis of lupus be made by clinical picture &high ana titer only?why don't other labs show positive?two rheum mds dx'd me.

A member asked:

Ana speckled pattern 1:80 with antigen detected for high sle titer, sjordens, high titers scleroderma, crest and pbc....how worried should i be?

A member asked:

Hx of seronegative ra yet recent labs show high crp/esr, absolute neutrophils and ana by ifa but w/ no titer. what could that mean without a titer?

A member asked:

I just got a blood test. i have high ast & alt levels, high bilrubin, a high ck total, and a positive ana titer. can you please help me identify this?

A member asked:

Sm/rnp 4.3, positive ana, positive ena, ana titer 1:1280 speckled, cytoplasmic positive but low titer 1:40. always high sed rate and c-reactive protein when i am in hospital. could this be mctd?

A member asked:

What could cause high sed rate (37), high wbc, high eosinophils, high neutrophils, a high ana (54.73), ana titer 1:40? chest pain, severe fatigue?

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