Question 1

is sickle cell anemia purely a genetic disorder?

Accepted Answer

I Don't Think So: I'm guessing a bit as to what you mean by your question. Sickle cell anemia is caused by a gene mutation on both copies of the beta globin gene. In that sense it is a genetic disease. However, a number of other factors, some of them environmental, can influence the type and severity of problems that patients with ssa have.

Question 2

what type of genetic disorder is sickle cell anemia or trait?

Accepted Answer

Hemoglobinopathy: Patients with sickle cell anemia make an abnormal hemoglobin (hgb.).  Normal HGB consists of paired protein chains (globin) and an iron containing part (heme).  Patients with ssa inherit an abnormal beta-globin gene from each parent.  Carriers have one normal beta-globin gene and one sickle beta globin gene.  The carriers (trait) have no symptoms.

Question 3

can you please tell me genetics of sickle cell anemia?

Accepted Answer

Inherited disease.: Sickle cell disease is genetic and is present at birth. It is inherited when a child receives two sickle cell genes—one from each parent.  This disease is more common in blacks (people of african heritage).  Sickle cell trait occurs when one sickle cell gene (“s”) is inherited from one parent and one normal gene (“a”) from the other.  Those with trait are "carriers" and are often asymptomatic.

Question 4

can the basic genetic defect of sickle cell anemia be treated?

Accepted Answer

Yes: A bone marrow transplant can replace the cells responsible for creating sickle cells with cells that produce normal hemoglobin. This is a very difficult and dangerous procedure that can lead to significant complications and death. This is why it is not routinely used to treat sickle cell anemia. Research is ongoing in attempts to have people with sickle cell anemia make normal blood cells.

Question 5

sickle cell anemia:is this birth defect only due to genetics?

Accepted Answer

Yes: It is a defect present from birth, yes. Would i call it a birth defect, no. It is a genetically derived abnormality in the metabolism of hemoglobin that results in sickling of the red cells under some circumstances. As a metabolic disease, it is inherited in a similar fashion to pku or cystic fibrosis. The term birth defect is more appropriate for a kid with malformation of an organ or body part.

Question 6

is sickle-cell anemia and malaria a virus or a bacteria spread disease?

Accepted Answer

See below: Sickle cell anemia is caused by a mutation in the beta-hemoglobin gene. The disease is inherited. Malaria is a disease caused by a parasite that infects red blood cells (rbcs), transmitted by the bite of infected mosquitoes. Sickle cell anemia is somewhat protective against malaria, since sickle cell disease shortens the lifespan of an rbc and interrupts the lifecycle of the malaria parasite.

Question 7

how is living with sickle cell anemia/disease?

Accepted Answer

There are: Huge ranges of disease severity and associated symptoms. Careful choices and attention to medical recommendations will improve the prognosis.

Question 8

if you suffer from a chronic pain disorder such as sickle cell anemia what natural pain relief is there?

Accepted Answer

Prevent ss crisis: Hydration, a lot of fluids, oxygenation, Folic Acid supplements, treat infection
new studies suggest sickle cell patient cannot vasodilate due to low nitric oxide--resveratrol, present in grapes, red wine increase nitric oxide! ---but I am skeptical.

Question 9

how do 2 people without sickle-cell anemia to have a child with sickle-cell disease?

Accepted Answer

Yes: The defect of sickle cell anemia occurs when 2 sickle cell genes are passed to a newborn. Since each parent passes half their genes at conception & it takes 2 sickle genes to cause disease, one gene comes from each parent. Many parents carry this gene quietly, unknown to them because it doesn't make a single gene carrier sick.

Question 10

my husband and i are both carriers of sickle cell anemia. what are our chances of our children exhibiting this disease?

Accepted Answer

Depends on genes: Two carrier parents have a 1/4 risk with each pregnancy of having a baby with a full blown sickle cell disorder. They have a 1/2 risk with each pregnancy of passing the carrier state, & a 1/4 chance that the baby would have neither. Many states test for sickle cell in their newborn screening programs so these kids can be identified early& precautions taken.

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Doctor answers about:

Sickle cell anemia genetic disorder

A member asked:

Is sickle cell anemia purely a genetic disorder?

A member asked:

What type of genetic disorder is sickle cell anemia or trait?

A member asked:

Can you please tell me genetics of sickle cell anemia?

A member asked:

Can the basic genetic defect of sickle cell anemia be treated?

A member asked:

Sickle cell anemia:is this birth defect only due to genetics?

A member asked:

Is sickle-cell anemia and malaria a virus or a bacteria spread disease?

A member asked:

How is living with sickle cell anemia/disease?

A member asked:

If you suffer from a chronic pain disorder such as sickle cell anemia what natural pain relief is there?

A member asked:

How do 2 people without sickle-cell anemia to have a child with sickle-cell disease?

A member asked:

My husband and i are both carriers of sickle cell anemia. what are our chances of our children exhibiting this disease?

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