Question 1

are there any rare genetic conditions that could occur if third cousins have children? do any specifically effect the height of those children?

Accepted Answer

Low risk but some: We are all thought to carry a few defective recessive genes.This has no importance because a good gene does enough work to prevent symptoms.You are more likely to share the same defective recessive genes with those closest to you genetically.Brother/sister are the closest, 1st cousins less &amp; 2nd cousins even less.When recessive genes pair up, metabolic diseases like PKU can show up.

Question 2

has anyone heard of a 40 yo suddenly growing several inches taller after hadn't grown in last 15 yrs? what rare genetic/med disorders would cause that

Accepted Answer

Endocrine issue: you should see an endocrinologist to have your growth hormone checked. there is a condition called acromegaly. usually facial fearures change too due to growth of the facial bones....

Question 3

what is incontinentia pigmenti - rare genetic condition?

Accepted Answer

Incontinentia: pigmenti is an uncommon inherited disorder of an incomplete IKBKG gene that causes increased tendency for certain body cells to self-destruct.  It is more common in women and primarily affects the skin, eyes, nails and teeth.  Most people are spared neurologic involvement, but delayed development, intellectual impairment and seizure may occur.

Question 4

anyone heard of incontinentia pigmenti a rare genetic condition?

Accepted Answer

Rare X linked pbm: Ip is a rare multisystem affliction that is seen  in girl infants & fatal to males in the womb. Incidence estimates run 1/40000-1-50000 births. It appears sometimes as a blistering rash, warty or just increased pigmentation in a swirling or streaking pattern. For a more see: www.Ncbi.Nlm.Nih.Gov/pmc/articles/
pmc2729954/?Tool=pmcentrez.

Question 5

can you please discuss the rare genetic disorders in children?

Accepted Answer

Too broad a topic: There are books written on the topic.If there is a critical enzyme pathway in the body there is likely a defect somewhere in that pathway. State screening tests commonly look for &gt; 25 different ones.

Question 6

where can i get information on some very rare genetic disorders?

Accepted Answer

The web & your doc: Three good sources are the centers for disease control website for genomic medicine (http://www.Cdc.Gov/genomics/), the national library of medicine's genetics home reference website (http://ghr.Nlm.Nih.Gov/), and the genetic alliance website (http://www.Geneticalliance.Org/). If you worry about yourself or a family member, the best place to start is with your personal physician.

Question 7

need expert help here. what are some very rare genetic disorders?

Accepted Answer

Many of them: There are numerous genetic disorders that are rare. A disease is defined rare in europe when it affects less than 1 in 2000, or in the usa when it affects less than 200, 000 americans at any given time. Some rare disorders happen only 1 in 5, 000, 000. Random examples of some rare conditions are: cantu syndrome, betaketothiolase deficiency, metachromatic leukodystrophy, alexander disease, etc.

Question 8

do any rare genetic disorders cause sudden change in height? brother grew 1 inch sometime after 23; when i hit 38 seemed to be about 3 inches taller.

Accepted Answer

I know: of no "genetic" disorder which would cause growth after the normal growth period is over.. HOWEVER ACROMEGALY ( a pituitary disease /growth) has been known to run in families. GOOGLE "Familial Isolated Pituitary Adenoma)
Hope this is helpful

Dr Z

Question 9

47yo friend says she's much taller than was few yrs ago(unsure of height b4 so can't compare). no phys changes. any rare genetic disorders cause that?

Accepted Answer

Yes: There are a few. Most common would probably be acromegaly. Please urge her to see a doctor. This is not a normal occurence.

Question 10

read online reports that rare genetic disorders can cause noticable growth spurts in 40yo adults w/no other physical changes. what are those disorders?

Accepted Answer

Growth spurts: It would be quite unusual for a 40 year old man to have growth spurts.
That does not mean he has no problems and he must see his Primary doctor as soon as possible.

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Rare genetic

A member asked:

Are there any rare genetic conditions that could occur if third cousins have children? do any specifically effect the height of those children?

A member asked:

Has anyone heard of a 40 yo suddenly growing several inches taller after hadn't grown in last 15 yrs? what rare genetic/med disorders would cause that

A member asked:

What is incontinentia pigmenti - rare genetic condition?

A member asked:

Anyone heard of incontinentia pigmenti a rare genetic condition?

A member asked:

Can you please discuss the rare genetic disorders in children?

A member asked:

Where can i get information on some very rare genetic disorders?

A member asked:

Need expert help here. what are some very rare genetic disorders?

A member asked:

Do any rare genetic disorders cause sudden change in height? brother grew 1 inch sometime after 23; when i hit 38 seemed to be about 3 inches taller.

A member asked:

47yo friend says she's much taller than was few yrs ago(unsure of height b4 so can't compare). no phys changes. any rare genetic disorders cause that?

A member asked:

Read online reports that rare genetic disorders can cause noticable growth spurts in 40yo adults w/no other physical changes. what are those disorders?

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